Impact of Serum Albumin Levels on Arterio-Venous Fistula Maturation in End-Stage Renal Disease Patients with Diabetes Mellitus
AVF Maturation in Hemodialysis Patients
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https://doi.org/10.5281/zenodo.7562218Keywords:
arteriovenous fistula, diabetes mellitus, hypoalbuminemia, hemodialysisAbstract
Background: Diabetes mellitus (DM) is a well-known risk factor for the prolongation of arterio-venous fistula (AVF) maturation and hypoalbuminemia. In this study, we studied the impact of the serum albumin levels during AVF creation on AVF maturation duration in diabetic patients.
Material and Methods: This single-center observational study was carried out using the data of 131 hemodialysis patients. Sixty-seven individuals with AVF were included in the study and were divided into two groups; diabetics and non-diabetics. Serum albumin levels during AVF creation were noted. The maturation period was described as the interval between the creation and cannulation time of AVF providing a minimum of 250 ml/min blood flow during the hemodialysis session (week). The demographic and clinical features of the individuals were noted and compared.
Results: Twenty-five individuals were in the diabetic and 42 were in the non-diabetic group. Serum albumin level was lower (3.50±0.44 vs 3.84±0.32) during AVF creation in the diabetic group; p<0.001. A negative correlation was observed between preoperative serum albumin level and AVF maturation time; p=0.003 and r=0,132. Additionally, maturation duration was significantly higher among diabetics (6.6 vs 5.1 weeks). Serum CRP levels were similar between the two groups (p=0.057).
Conclusion: Longer AVF maturation time in diabetic patients is closely related to low serum albumin levels. Low serum levels of albumin should be considered when evaluating ESRD patients with DM for AVF creation.
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