Dandy Walker Malformation in a Patient Presenting with Hyponatremia

Dandy Walker and Hyponatremia


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Authors

DOI:

https://doi.org/10.5281/zenodo.17450717

Keywords:

Dandy-Walker Syndrome, Hyponatremia, Kidney Diseases

Abstract

Hyponatremia is defined as a serum sodium concentration of less than 135 mmol/L and is a common electrolyte abnormality. The most common causes of hyponatremia following central nervous system disorders are syndrome of inappropriate antidiuretic hormone secretion (SIADH) and cerebral salt wasting (CSW). In this case report, we discuss the diagnosis and treatment of CSW in a 30-year-old male patient with recurrent episodes of hyponatremia, in the context of the literature. CSW develops after central nervous system disorders and is characterized by hypovolemia, low serum osmolality, high urine osmolality, and high urine sodium levels.

References

Oria MS, Rasib AR, Pirzad AF, Wali Ibrahim Khel F, Ibrahim Khel MI, Wardak FR. A Rare Case of Dandy-Walker Syndrome. Int Med Case Rep J. 2022;15:55-59. Published 2022 Feb 15. doi:10.2147/IMCRJ.S350858

Society for Maternal-Fetal Medicine (SMFM), Monteagudo A. Dandy-Walker Malformation. Am J Obstet Gynecol. 2020;223(6):B38-B41. doi:10.1016/j.ajog.2020.08.184

Momi J, Tang CM, Abcar AC, Kujubu DA, Sim JJ. Hyponatremia-what is cerebral salt wasting?. Perm J. 2010;14(2):62-65. doi:10.7812/TPP/08-066

Adrogué HJ, Tucker BM, Madias NE. Diagnosis and Management of Hyponatremia: A Review. JAMA. 2022;328(3):280-291. doi:10.1001/jama.2022.11176

Lindner G, Schwarz C, Haidinger M, Ravioli S. Hyponatremia in the emergency department. Am J Emerg Med. 2022;60:1-8. doi:10.1016/j.ajem.2022.07.023

Decaux G. Morbidity Associated with Chronic Hyponatremia. J Clin Med. 2023;12(3):978. Published 2023 Jan 27. doi:10.3390/jcm12030978

Yee AH, Burns JD, Wijdicks EF. Cerebral salt wasting: pathophysiology, diagnosis, and treatment. Neurosurg Clin N Am. 2010;21(2):339-352. doi:10.1016/j.nec.2009.10.011

Moritz ML. Syndrome of inappropriate antidiuresis and cerebral salt wasting syndrome: are they different and does it matter?. Pediatr Nephrol. 2012;27(5):689-693. doi:10.1007/s00467-012-2112-1

Elledge SR, Shewmaker JW, Yang S, Blunck JR. Fludrocortisone evaluation in aneurysmal subarachnoid hemorrhage patients with cerebral salt wasting (Flush Salt). Clin Neurol Neurosurg. 2023;225:107568. doi:10.1016/j.clineuro.2022.107568

Chendrasekhar A, Chow PT, Cohen D, et al. Cerebral Salt Wasting in Traumatic Brain Injury Is Associated with Increased Morbidity and Mortality. Neuropsychiatr Dis Treat. 2020;16:801-806. Published 2020 Mar 25. doi:10.2147/NDT.S233389

Di Nora A, Costanza G, Pizzo F, et al. Dandy-Walker malformation and variants: clinical features and associated anomalies in 28 affected children-a single retrospective study and a review of the literature. Acta Neurol Belg. 2023;123(3):903-909. doi:10.1007/s13760-022-02059-z

Li C, Mabry I, Khan YR, Balsz M, Hanson RJ, Siddiqi J. Hydrocephalus-Associated Hyponatremia: A Review. Cureus. 2022;14(2):e22427. Published 2022 Feb 21. doi:10.7759/cureus.22427

Liangos O, Madias NE. Severe symptomatic hyponatremia due to cerebral salt wasting syndrome in a patient with traumatic head injury and Dandy-Walker malformation of the brain. Clin Nephrol Case Stud. 2021;9:4-10. Published 2021 Feb 19. doi:10.5414/CNCS110146

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Published

2025-10-27

How to Cite

Hüzmeli, C. (2025). Dandy Walker Malformation in a Patient Presenting with Hyponatremia: Dandy Walker and Hyponatremia. Journal of European Internal Medicine Professionals, 3(4), 175–177. https://doi.org/10.5281/zenodo.17450717