Evaluation of Thyroid Functions and Correlation of Body Mass Index with Apnea-Hypopnea Index in Patients with Obstructive Sleep Apnea Syndrome
Thyroid Functions and Apnea-Hypopnea Index
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https://doi.org/10.5281/zenodo.8135153Keywords:
OSAS, thyroid, BMI, hypothyroidismAbstract
Background: Thyroid hormone deficiency and excessive weight, which are considered endocrine disorders, can be easily detected, have low cost, and guide treatment planning in obstructive sleep apnea syndrome (OSAS). We examined thyroid hormone levels in patients diagnosed with OSAS using polysomnography and conducted a study to investigate the correlation between body mass index (BMI) values and apnea-hypopnea index (AHI).
Material and Methods: This study included patients who presented to the Ear, Nose, and Throat Clinic and Sleep Disorders Center of Dicle University Faculty of Medicine Hospital between July 2008 and November 2010, and were diagnosed with OSAS based on polysomnography (PSG) results. The study group consisted of a heterogeneous group in terms of presenting complaints, with most patients reporting complaints of snoring, while others had a history of witnessed apneas by their partners, excessive daytime sleepiness, fatigue, and headaches. From the group diagnosed with OSAS (AHI>5) based on PSG results, the first 100 randomly selected patients were included in the study.
Results: The mean age of the cases diagnosed with OSAS based on PSG results was 48.79±10.70. The age of women ranged from 24 to 76, with a mean age of 55.44±19.25. The age of men ranged from 24 to 77, with a mean age of 46.33±15.48. Among the 100 patients, 33 had mild, 19 had moderate, and 48 had severe OSAS. Among these 100 cases, hypothyroidism was detected in 5 patients (2 with mild OSAS and 3 with severe OSAS) based on serum thyroid hormone levels. Among the patients with hypothyroidism, 2 were female and 3 were male. In all cases, a positive correlation was found between BMI and AHI, with a significance level of 45.9% and a statistically significant correlation.
Conclusion: Based on these findings, it can be concluded that screening for hypothyroidism and measuring BMI should be necessary for all patients presenting to sleep laboratories with suspected OSAS.
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